World's First Baby Born From Deceased Donor's Transplanted Uterus

The report of a Brazilian woman giving birth to a healthy baby girl a year ago, post a 10-hour long uterus transplant surgery, has added another feather in the medical world's cap and given a ray of hope to women with uterus infertility. The demonstrated success of a procedure involving a deceased donor, he says, may spare live donors from undergoing risky procedures, and make transplants possible for far more women.

The uterus transplant, in this case, happened in September 2016.

Besides saving the life of patients with failed vital organs, scientists have also conducted hand or face transplants in recent years to improve a person's quality of life.

The surgical team had to connect the donor's uterus with the veins, arteries, ligaments, and vaginal canal of the recipient.

The recipient had her first menstruation 37 days after the uterus transplant, and continued to have regular cycles after that.

A team of doctors in Brazil have announced a medical first that could someday help countless women unable to have children because of a damaged or absent uterus. "While uterine transplantation sounds extreme, it can be indicated in women born without a uterus, or in women who have a non-functional or surgically-absent uterus".

But the outcomes and effects of donations from live and deceased donors are yet to be compared. There have been previous attempts to birth a child using a transplanted uterus from a deceased donor, however, all have proved unsuccessful.

Pregnancy was confirmed 10 days after implantation.

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Doctors say the woman had a healthy and fairly typical pregnancy, before giving birth via c-section to a six-pound baby girl a year ago.

Before the new breakthrough, uterus transplantation from living donors has proven successful in a couple of cases.

"The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility."the lancet quoted the lead researcher Dr Dani Ejzenberg, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo". Until now, the only successful uterus transplants have involved living donors who are typically family members of the recipients.

The first baby has been born using the transplanted womb from a dead woman, and British doctors say they are planning to replicate the procedure in the UK.

The early embryos produced by IVF treatment had been frozen and stored four months before the transplant.

"The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population", he added. The mother and child managed to leave the hospital just three days after the birth, with a gloriously uneventful following few months. When the researchers wrote the paper describing the case - about seven months after the birth - both mom and the baby girl were healthy. Upon encountering a suitable candidate and donor, doctors must act quickly to remove the uterus and transport it to the patient.

The first childbirth following uterine transplantation from living donors occurred in Sweden in September 2013. The baby was born on December 15, 2017, through a C-section, and is believed to be the first to be born with a uterus from a deceased donor. According to the authors of the case study, around one in 500 women have infertility associated with the womb.

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