Coronavirus: UK to test inhaled vaccines

Close on the heels of the AZ statement, Serum Institute of India said, "Once (the) DCGI (Drug Controller General of India) gives us the permission to restart the trials in India, we will resume the trials".

However, the latest note added, "AstraZeneca and the University of Oxford, as the trial sponsor, can not disclose further medical information".

On September 6, the standard review process in the ongoing trials of the vaccine candidate triggered a "voluntary pause to vaccination" across global sites so that independent committees and worldwide regulators could review safety data related to the vaccine, AstraZeneca said. The UK committee has concluded its investigations and recommended to the MHRA that trials in the UK are safe to resume, it added.

Larger studies of the Imperial and Oxford vaccine are already under way, but this study aims to see if the vaccines might be more effective if they are inhaled.

The fact that some pharmaceutical companies delegate the risks associated with their vaccines to countries which buy them raises additional questions, the RDIF chief said.

Despite the intense attention on the development of this particular COVID-19 vaccine, it is important to note these kinds of clinical trial pauses are routine.

50 killed in DR Congo mine collapse
The cause of the landslide is now under investigation. "The authorities must take responsibility instead of taxing" these miners. South Kivu governor Theo Ngwabidje Kasi who confirmed the incident said about "50 people, majority young" died.

Speaking with PUNCH HealthWise in an exclusive interview, the physician said Russian Federation "jumped the gun" by hastily approving the vaccine for use, without completing the processes vaccines undergo before they're considered safe for public use.

Britain has secured access to up to 190 million doses of a potential coronavirus vaccine from Valneva in deal worth as much as 1.37 billion euros, the French-Austrian vaccine firm said Monday.

"This new agreement could help us vaccinate millions of people across the country, as well as help create a United Kingdom vaccine manufacturing facility to speed up access to a potential Covid-19 candidate and boost the country's resilience against future pandemics", said Britain's Business Secretary Alok Sharma.

The human trials resumed days after a pause had been announced in the trials after an adverse reaction in one of the participants. Volunteers from some of the worst affected countries - Britain, Brazil, South Africa and the USA - are taking part in the trial.

After vaccination, the surface spike protein is produced, priming the immune system to attack the SARS-CoV-2 virus if it later infects the body.

"It may well be that one group has the right vaccine but the wrong delivery method, and only trials such as this will be able to tell us that", said Robin Shattock, who is leading the development of Imperial's vaccine. The declaration, though came late, also triggered a race to find a medicine and a vaccine for the disease. However, these trials, experts say, were limited in nature with just few participants to attest to its efficacy and ally the safety concerns.

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